Cleveland, OH (My Sportsbook) - Andre Miller tied a season-high with 30 points while also dishing out eight assists, as the Philadelphia 76ers defeated the Cavaliers' reserves, 111-110, denying Cleveland a chance to match the best regular season home record in NBA history.

Even with MVP candidate LeBron James and fellow Cleveland regulars Mo Williams, Zydrunas Ilgauskas and Joe Smith resting for the playoff run, the Sixers (41-41) struggled to snap a season-high six-game losing streak.

But coupled with Chicago's loss to Toronto Wednesday, Philly is the No. 6 seed in Eastern Conference standings and will play third-seeded Orlando in the first round of the playoffs.

Cleveland (66-16), meanwhile, lost just their second bout at Quicken Loans Arena this season, falling short of tying the 1985-86 Celtics' 40-1 home mark. The Lakers handed the East's top seed their only other home defeat back on February 8.

Daniel Gibson led the short-handed attack with 28 points, including the game- tying three-pointer just prior to the regulation buzzer. The Cavs, the owners of the best record in the league, will face the Detroit Pistons in the opening round of the postseason.